1–4 Parkinson’s disease is a neurodegenerative condition related to a decrease in dopamine neurons in the substantia nigra. In the United States, the number of persons with Parkinson’s disease is expected to increase from the approximately 340,000 in 2005 to 610,000 in 2030. Keywords: diagnosis of Parkinson’s disease, timed up and go, clinical biomarker of pd IntroductionĪs our population ages, there is an increasing incidence and prevalence of Parkinson’s disease (PD). The dual task instrumental iTUG variant of the TUG may be more sensitive as a clinical biomarker for distinguishing individuals with early PD from age matched controls. However, age matched controls were significantly less depressed, had better balance confidence but reported significantly less physical activity, more medical problems and more prescription medications.ĭiscussion & conclusion: The TUG was not a clinically sensitive biomarker to distinguish age matched healthy participants from those with mild-moderate PD who exercised aggressively. In addition, no significant differences were found between the two groups relative to gender, age, pain, fall history or gait speed. Results: TUG performance was within normal limits with no significant differences between the two groups (7.28 seconds age matched controls and 7.60 seconds PD). Dependent variables were described (mean and standard deviation) and group differences tested for significance with the Two Sample T Test (P<0.05). Seventy percent of participants returned to be tested with the instrumental, dual task TUG (i TUG), the Five Times Sit to Stand Test (FTSTS) and 360o turning. Dependent variables included gender, age, self-reported motor and non-motor impairments paired with standardized measurements of mobility, balance (TUG) and cognition. Methods: This descriptive, cross sectional evaluation study included 30 participants (15 with mild to moderate PD and 15 age matched controls. Could the clinical Timed Up and Go (TUG) test serve as an inexpensive, clinical biomarker to help physicians make a diagnosis of PD? Given there are no laboratory tests to rule in the disorder, the diagnosis may be delayed until 85% of the dopamine neurons are degenerated.
DOI: 10.15406/ipmrj.204īackground: As the population ages, an increasing number of individuals are diagnosed with Parkinson’s Disease (PD), a complex, progressive, neurodegenerative motor and nonmotor disorder which can compromise quality of life/ independence. Is the timed up and go (TUG) sensitive to differentiating patients with mild to moderate PD compared to age matched controls: a descriptive pilot study. Please type the correct Captcha word to see email ID.ġDepartment of Physical Therapy and Rehabilitation Science, UCSF School of Medicine, USAĢDepartment of Neurology, UCSF School of Medicine, USAģDepartment Graduate Student in the UCSF Graduate Division, UCSF/SFSU Graduate Program in Physical Therapy, USAĤNeurologist and Specialist in Parkinson?s disease in the Pennisula Private Neurology Practice, USAĬorrespondence: Nancy Byl, Department of Physical Therapy and Rehabilitation Science, Professor Emeritus in the UCSF School of Medicine, USA, Tel 4155144816, Fax 4155144817Ĭitation: Byl N, Henry R, Rizzo R, et al. Regret for the inconvenience: we are taking measures to prevent fraudulent form submissions by extractors and page crawlers.
0 kommentar(er)
